
Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment. Pereira NRC, Loiola RA, Rodrigues SF et al. Production of isotonic, sterile, and kinetically stable lipid-core nanocapsules for injectable administration. Chemical stability mass loss and hydrolysis mechanism of sterile and non-sterile lipid-core nanocapsules: the influence of the molar mass of the polymer wall. Calgaroto S, Fauri LE, Frank LA, Paese K, Guterres SS, Pohlmann AR. Sustained release from lipid-core nanocapsules by varying the core viscosity and the particle surface area. Couvreur P, Barratt G, Fattal E, Legrand P, Vauthier C. Describes that coated lipid nanocapsules (LNC) impact on the immune cell response is strongly correlated to their coating.

Immune cell impact of three differently coated lipid nanocapsules: pluronic, chitosan and polyethylene glycol. Farace C, Sánchez-Moreno P, Orecchioni M et al. Cancer nanomedicine and the complement system activation paradigm: anaphylaxis and tumour growth. Shows nanoliposomes may have immunosuppressive and angiogenetic properties, directly counterbalancing their anticancer activity.Liposome promotion of tumor growth is associated with angiogenesis and inhibition of antitumor immune responses. Liposome-induced immunosuppression and tumor growth is mediated by macrophages and mitigated by liposome-encapsulated alendronate. Meta-analysis of clinical and preclinical studies comparing the anticancer efficacy of liposomal versus conventional non-liposomal doxorubicin. Petersen GH, Alzghari SK, Chee W, Sankari SS, La-Beck NM. Progress in nanomedicine: approved and investigational nanodrugs. Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Bobo D, Robinson KJ, Islam J, Thurecht KJ, Corrie SR. Papers of special note have been highlighted as:
